To play the Resident Evil 4 Cheat Edition ISO, you'll need to:

Using a PS2 with Open PS2 Loader (OPL) or a similar homebrew tool allows you to load the ISO from a USB or internal hard drive.

The Resident Evil 4 Cheat Edition ISO is a modified version of the original Resident Evil 4 game, which was released in 2005 for the PlayStation 2, Xbox, and Microsoft Windows. This cheat edition is an ISO file that contains the game's data, including cheats, hacks, and modifications that allow players to access infinite ammo, health, and other perks.

Release Group: [Anonymous] Region: NTSC-U / PAL

(in all versions)

That said, I can help you understand what these versions typically contain and how to achieve similar effects legally: